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Multiple Choice

At what temperature are coagulation specimens kept?

Temperature control is crucial for coagulation testing because clotting factor activity is temperature dependent. Keeping the specimen at room temperature preserves factor stability without speeding up or altering reactions that would happen at other temperatures. Refrigeration at 4°C can change factor activity and affect results, freezing at -20°C can denature proteins, and incubating at 37°C would accelerate clotting and distort results. Room temperature provides a practical balance and is the standard for routine coagulation specimens.

Temperature control is crucial for coagulation testing because clotting factor activity is temperature dependent. Keeping the specimen at room temperature preserves factor stability without speeding up or altering reactions that would happen at other temperatures. Refrigeration at 4°C can change factor activity and affect results, freezing at -20°C can denature proteins, and incubating at 37°C would accelerate clotting and distort results. Room temperature provides a practical balance and is the standard for routine coagulation specimens.