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Multiple Choice

Hemophilia C treatment option includes which of the following?

Hemophilia C is a deficiency of Factor XI, so the treatment goal is to replace Factor XI. The best options to do this are products that contain Factor XI: Factor XI concentrate or fresh frozen plasma, since FFP provides Factor XI along with other coagulation factors. Desmopressin mainly raises factor VIII and von Willebrand factor, so it’s not effective for Factor XI deficiency. Prothrombin complex concentrates supply vitamin K–dependent factors II, VII, IX, and X and do not provide Factor XI. Factor IX concentrate treats Factor IX deficiency (Hemophilia B), not Factor XI. So using Factor XI–containing products directly addresses the specific missing factor, making that choice the correct approach.

Hemophilia C is a deficiency of Factor XI, so the treatment goal is to replace Factor XI. The best options to do this are products that contain Factor XI: Factor XI concentrate or fresh frozen plasma, since FFP provides Factor XI along with other coagulation factors. Desmopressin mainly raises factor VIII and von Willebrand factor, so it’s not effective for Factor XI deficiency. Prothrombin complex concentrates supply vitamin K–dependent factors II, VII, IX, and X and do not provide Factor XI. Factor IX concentrate treats Factor IX deficiency (Hemophilia B), not Factor XI. So using Factor XI–containing products directly addresses the specific missing factor, making that choice the correct approach.