How is hemophilia C treated?

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Multiple Choice

How is hemophilia C treated?

Hemophilia C is a deficiency of factor XI, which is part of the intrinsic coagulation pathway. Because the missing factor XI needs to be replaced to correct bleeding risk, the most direct treatment is factor XI replacement, using a factor XI concentrate. If a dedicated FXI product isn’t available, fresh frozen plasma can be used because it contains FXI along with other coagulation factors to help hemostasis. Desmopressin raises levels of factor VIII and von Willebrand factor, not factor XI, so it is not effective for FXI deficiency. A factor IX concentrate targets factor IX and treats hemophilia B, not FXI deficiency. Prothrombin complex concentrates provide factors II, IX, X, and VII and do not reliably replace factor XI, making them unsuitable as the standard treatment for hemophilia C.

Hemophilia C is a deficiency of factor XI, which is part of the intrinsic coagulation pathway. Because the missing factor XI needs to be replaced to correct bleeding risk, the most direct treatment is factor XI replacement, using a factor XI concentrate. If a dedicated FXI product isn’t available, fresh frozen plasma can be used because it contains FXI along with other coagulation factors to help hemostasis. Desmopressin raises levels of factor VIII and von Willebrand factor, not factor XI, so it is not effective for FXI deficiency. A factor IX concentrate targets factor IX and treats hemophilia B, not FXI deficiency. Prothrombin complex concentrates provide factors II, IX, X, and VII and do not reliably replace factor XI, making them unsuitable as the standard treatment for hemophilia C.

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