In the RBC histogram, RBCs are measured directly from which size range?

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Multiple Choice

In the RBC histogram, RBCs are measured directly from which size range?

RBC histogram is built by sizing cells and plotting how many red cells fall into each volume bin. The sizing is done using the impedance (Coulter) method, so each pulse reflects a cell’s volume. The instrument defines a window of sizes that are considered red blood cells. This window is about 24 to 360 femtoliters. It’s set this way to exclude very small particles like platelets (which are typically 2–20 fL) and to avoid including unusually large debris or cell fragments that aren’t normal RBCs. Most mature RBCs fall within this range, with macrocytes extending toward the upper end but still within the window. Therefore, the RBC histogram directly measures cells in the 24–360 fL range.

RBC histogram is built by sizing cells and plotting how many red cells fall into each volume bin. The sizing is done using the impedance (Coulter) method, so each pulse reflects a cell’s volume. The instrument defines a window of sizes that are considered red blood cells. This window is about 24 to 360 femtoliters. It’s set this way to exclude very small particles like platelets (which are typically 2–20 fL) and to avoid including unusually large debris or cell fragments that aren’t normal RBCs. Most mature RBCs fall within this range, with macrocytes extending toward the upper end but still within the window. Therefore, the RBC histogram directly measures cells in the 24–360 fL range.

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