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Multiple Choice

In the WBC histogram, which threshold is used to capture larger cells?

In the WBC histogram, cell size is used to separate leukocyte populations. Lymphocytes are typically smaller, while larger leukocytes such as neutrophils and monocytes have greater volume. The threshold around 35 fL serves to distinguish these groups by placing most small cells below this value and larger cells above it. By using a cutoff of >35 fL, the histogram effectively captures the larger cells in the higher-volume region, which is important for accurate differential counts and for spotting shifts toward larger leukocytes. If the cutoff were much lower, small cells and debris would blur the large-cell region; if it were much higher, many ordinarily large WBCs would be missed.

In the WBC histogram, cell size is used to separate leukocyte populations. Lymphocytes are typically smaller, while larger leukocytes such as neutrophils and monocytes have greater volume. The threshold around 35 fL serves to distinguish these groups by placing most small cells below this value and larger cells above it. By using a cutoff of >35 fL, the histogram effectively captures the larger cells in the higher-volume region, which is important for accurate differential counts and for spotting shifts toward larger leukocytes. If the cutoff were much lower, small cells and debris would blur the large-cell region; if it were much higher, many ordinarily large WBCs would be missed.