What is the reagent in the PT test?

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Multiple Choice

What is the reagent in the PT test?

The main idea here is that the PT test needs a reagent that can start the extrinsic pathway by providing tissue factor, a surface for coagulation factors to assemble, and calcium ions to drive the reaction. Thromboplastin supplies tissue factor, the phospholipid provides the membrane surface, and calcium chloride supplies the calcium. All three components are required for a reliable PT result, so the reagent that includes thromboplastin, phospholipid, and calcium chloride is the correct choice. Thromboplastin alone misses calcium and the phospholipid surface; calcium chloride alone lacks tissue factor; phospholipid alone lacks tissue factor and calcium.

The main idea here is that the PT test needs a reagent that can start the extrinsic pathway by providing tissue factor, a surface for coagulation factors to assemble, and calcium ions to drive the reaction. Thromboplastin supplies tissue factor, the phospholipid provides the membrane surface, and calcium chloride supplies the calcium. All three components are required for a reliable PT result, so the reagent that includes thromboplastin, phospholipid, and calcium chloride is the correct choice. Thromboplastin alone misses calcium and the phospholipid surface; calcium chloride alone lacks tissue factor; phospholipid alone lacks tissue factor and calcium.

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