What is the recommended recollection anticoagulant and correction factor when EDTA causes platelet clumping?

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Multiple Choice

What is the recommended recollection anticoagulant and correction factor when EDTA causes platelet clumping?

When EDTA causes platelets to clump, the platelet count can appear falsely low in an EDTA tube. Recollecting in sodium citrate avoids the EDTA‑induced clumping and gives a more accurate platelet count. However, citrate tubes dilute the blood sample about 10% due to the 1:9 blood-to-anticoagulant ratio, so you must correct the measured count by multiplying by 1.1 to estimate the true value. Heparin isn’t the standard choice for routine CBC recollection, and using EDTA with vitamin C or potassium oxalate isn’t the appropriate remedy for this issue.

When EDTA causes platelets to clump, the platelet count can appear falsely low in an EDTA tube. Recollecting in sodium citrate avoids the EDTA‑induced clumping and gives a more accurate platelet count. However, citrate tubes dilute the blood sample about 10% due to the 1:9 blood-to-anticoagulant ratio, so you must correct the measured count by multiplying by 1.1 to estimate the true value. Heparin isn’t the standard choice for routine CBC recollection, and using EDTA with vitamin C or potassium oxalate isn’t the appropriate remedy for this issue.

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