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Multiple Choice

Which pathway is the main energy source in cells like red blood cells?

Red blood cells rely on glycolysis in the cytosol to generate ATP because they lack mitochondria and cannot perform oxidative phosphorylation. The Embden-Meyerhof pathway converts glucose to pyruvate with a net yield of 2 ATP per glucose, providing the energy needed to power membrane ion pumps and maintain cell shape. The pentose phosphate pathway mainly produces NADPH and ribose-5-phosphate, not ATP. The Luebering-Rapoport pathway diverts some glycolytic intermediates to make 2,3-bisphosphoglycerate, which modulates oxygen release rather than supplying energy. The methemoglobin reductase pathway uses NADH to keep hemoglobin in the ferrous state, not energy production. So, the Embden-Meyerhof pathway is the primary energy source in red blood cells.

Red blood cells rely on glycolysis in the cytosol to generate ATP because they lack mitochondria and cannot perform oxidative phosphorylation. The Embden-Meyerhof pathway converts glucose to pyruvate with a net yield of 2 ATP per glucose, providing the energy needed to power membrane ion pumps and maintain cell shape. The pentose phosphate pathway mainly produces NADPH and ribose-5-phosphate, not ATP. The Luebering-Rapoport pathway diverts some glycolytic intermediates to make 2,3-bisphosphoglycerate, which modulates oxygen release rather than supplying energy. The methemoglobin reductase pathway uses NADH to keep hemoglobin in the ferrous state, not energy production. So, the Embden-Meyerhof pathway is the primary energy source in red blood cells.